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There are several matches for 'probable protein methyltransferase'.
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1580 matches
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organism
protein
1)
Homo sapiens
METTL15 -
Probable
methyltransferase
-like
protein
15;
Probable
S-adenosyl-L-methionine-dependent
methyltransferase
.
[a.k.a. NM_152636.3, XM_017017303.2, BAC03631.1]
2)
Homo sapiens
METTL18 - Histidine
protein
methyltransferase
1 homolog;
Probable
histidine
methyltransferase
; Belongs to the
methyltransferase
superfamily. METTL18 family.
[a.k.a. ENST00000303469, Arsenic-transactivated protein 2, ENSG00000171806]
3)
Homo sapiens
METTL5 -
Methyltransferase
-like
protein
5;
Probable
methyltransferase
.
[a.k.a. ENSP00000307903, NP_001280116, ENST00000260953.9]
4)
Homo sapiens
METTL7B -
Methyltransferase
-like
protein
7B;
Probable
methyltransferase
.
[a.k.a. MGC17301, NP_689850.2, A0A087WZT2]
5)
Homo sapiens
METTL7A -
Methyltransferase
-like
protein
7A;
Probable
methyltransferase
.
[a.k.a. ENST00000547104, EAW58154.1, ENSP00000404638]
6)
Homo sapiens
METTL23 -
Methyltransferase
-like
protein
23;
Probable
methyltransferase
.
[a.k.a. OTTHUMG00000180371, Q86XA0, XP_006721741]
7)
Homo sapiens
SETD3 - Actin-histidine N-
methyltransferase
;
Protein
-histidine N-
methyltransferase
that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have
protein
-lysine N-
methyltransferase
activity and
probably
only catalyzes histidine methylation of actin.
[a.k.a. SET domain-containing protein 3, SETD3-204, C14orf154]
8)
Homo sapiens
PRDM8 - PR domain zinc finger
protein
8;
Probable
histone
methyltransferase
, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity); Belongs to the class V-like SAM-binding methyltrans [...]
[a.k.a. NM_020226, uc003hmb.5, PR/SET domain 8]
9)
Homo sapiens
BUD23 -
Probable
18S rRNA (guanine-N(7))-
methyltransferase
; S-adenosyl-L-methionine-dependent
methyltransferase
that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the
methyltransferase
adapter
protein
TRM112 for full rRNA
methyltransferase
activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its
methyltransferase
activity. Locus-specific steroid receptor coactivator. Potentiates transactivat [...]
[a.k.a. H7C170, ENST00000423497, 2.1.1.309]
10)
Homo sapiens
KMT5A - N-lysine
methyltransferase
KMT5A;
Protein
-lysine N-
methyltransferase
that monomethylates both histones and non-histone
proteins
. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation,
probably
by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper [...]
[a.k.a. NP_001311433.1, R-HSA-69278, KMT5A-202]
11)
Homo sapiens
LCMT2 - tRNA wybutosine-synthesizing
protein
4;
Probable
S-adenosyl-L-methionine-dependent
methyltransferase
that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues; Belongs to the
methyltransferase
superfamily. LCMT family.
[a.k.a. EC 2.1.1.290, HPA039401, 9836]
12)
Homo sapiens
ANTKMT - Adenine nucleotide translocase lysine N-
methyltransferase
; Mitochondrial
protein
-lysine N-
methyltransferase
that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration.
Probably
also trimethylates ANT1/SLC25A4.
[a.k.a. 65990, H3BQW1, ANT-KMT]
13)
Homo sapiens
TYW3 - tRNA wybutosine-synthesizing
protein
3 homolog;
Probable
S-adenosyl-L-methionine-dependent
methyltransferase
that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity); Belongs to the TYW3 family.
[a.k.a. XP_006710410.1, uc001dgn.4, AAH71765.1]
14)
Homo sapiens
CTCFL - Transcriptional repressor CTCFL; Testis-specific DNA binding
protein
responsible for insulator function, nuclear architecture and transcriptional control, which
probably
acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7
methyltransferase
, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This
probably
leads to recruit de novo DNA
methyltransferases
a [...]
[a.k.a. DQ778116, ENSP00000476398, OMIM:607022]
15)
Homo sapiens
MBD1 - Methyl-CpG-binding domain
protein
1; Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone
methyltransferase
SETDB1.
Probably
forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylat [...]
[a.k.a. XP_024306944.1, AAD50371.1, XP_016881249.1]
16)
Homo sapiens
SPOUT1 - Putative
methyltransferase
C9orf114; Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation
probably
by recruiting A-kinase anchor
protein
AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level.
[a.k.a. ENST00000466556, Centromere protein 32, C9orf114]
17)
Homo sapiens
ATF7IP - Activating transcription factor 7-interacting
protein
1; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-mediated heterochromatin formation and gene silencing. Mediates MBD1-dependent transcriptional repression,
probably
by recruiting complexes containing SETDB1. Stabilizes SETDB1, is required to stimulate histone
methyltransferase
activity of SETDB1 and facilitates the conversion of dimethylate [...]
[a.k.a. UPI000204AB35, ENST00000535179, XM_017019638.1]
18)
Homo sapiens
EHMT1 - Histone-lysine N-
methyltransferase
EHMT1; Histone
methyltransferase
that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1
proteins
to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone
methyltransferase
activity is not required for DNA methylation, suggesting that these 2 activities function independently.
Probably
targeted to histone H3 by different DNA-binding [...]
[a.k.a. ENST00000635741.1, EHMT1-247, A0A0D9SFG7]
19)
Homo sapiens
RBL2 - Retinoblastoma-like
protein
2; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone
methyltransferases
KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation.
Probably
acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially [...]
[a.k.a. XM_011523253, R-HSA-1362300, R-HSA-69278]
20)
Homo sapiens
RBL1 - Retinoblastoma-like
protein
1; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation (By similarity). Recruits and targets histone
methyltransferases
KMT5B and KMT5C, leading to epigenetic transcriptional repression (By similarity). Controls histone H4 'Lys-20' trimethylation (By similarity).
Probably
acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters (By similarity). Potent inhib [...]
[a.k.a. R-HSA-170834, RBL1-202, R-HSA-1362300]
1580 matches
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